β-thujaplicin (CAS# 499-44-5)

Chemical Property:

Molecular Formula	C10H12O2
Molar Misa	164.2
Kuchulukana	1.0041 (kuyerekeza movutikira)
Melting Point	50-52°C(kuyatsa)
Boling Point	140°C10mm Hg(kuyatsa)
Pophulikira	128.1°C
Kusungunuka	Zosasungunuka m'madzi
Kuthamanga kwa Vapor	8.98E-05mmHg pa 25°C
Maonekedwe	Makhiristo opanda mtundu, a prismatic (opangidwanso kuchokera ku ethanol ya anhydrous)
Mtundu	Choyera
Merck	14,9390
pKa	7.06±0.30 (Zonenedweratu)
Mkhalidwe Wosungira	Osindikizidwa muuma, Kutentha Kwapachipinda
Kukhazikika	Kukhazikika kwa chaka chimodzi kuyambira tsiku lomwe mwagula monga momwe zaperekedwa. Mayankho a DMSO kapena ethanol amatha kusungidwa pa -20 ° kwa miyezi inayi.
Zomverera	Pewani kukhudzana ndi ma oxides
Refractive Index	1.5190 (chiyerekezo)
MDL	Mtengo wa MFCD00059582
Maphunziro a in vitro	Mu U87MG ndi T98G glioma cell mizere, hinokitiol imasonyeza kuchepa kwa mlingo wodalira mlingo, ndi IC 50 miyeso ya 316.5 ± 35.5 ndi 152.5 ± 25.3 µM, motsatira. Hinokitiol imachepetsa ntchito ya ALDH komanso kuthekera kodzikonzanso m'maselo a glioma, ndikuletsa mu vitro oncogenicity. Hinokitiol imachepetsanso mawu a Nrf2 m'maselo a glioma m'njira yodalira mlingo. Hinokitiol (0-100 μM) imalepheretsa kukula kwa maselo a khansa ya m'matumbo pamlingo wotengera nthawi komanso nthawi. Hinokitiol (5, 10 μM) imachepetsa DNMT1 ndi UHRF1 mRNA ndi kufotokoza kwa mapuloteni, ndikuwonjezera mawu a TET1 pogwiritsa ntchito kupititsa patsogolo kwa 5hmC mu maselo a HCT-116. Komanso, hinokitiol imachepetsa methylation ndikubwezeretsa mRNA mawu a MGMT, CHST10, ndi majini a BTG4.

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Zizindikiro Zowopsa	Xn - Zowopsa
Zizindikiro Zowopsa	22 - Zowopsa ngati zitamezedwa
Kufotokozera Zachitetezo	36 - Valani zovala zoyenera zodzitetezera.
WGK Germany	3
Mtengo wa RTECS	GU4200000

Mawu Oyamba

Hinokiol, yemwe amadziwikanso kuti α-terpene mowa kapena Thujanol, ndi chilengedwe chachilengedwe chomwe chili m'modzi mwa zigawo za turpentine. Hinoylol ndi madzi opanda mtundu, owoneka bwino komanso onunkhira a paini.

Hinokiol ali ndi ntchito zosiyanasiyana. Amagwiritsidwa ntchito kwambiri m'makampani opanga mafuta onunkhira komanso onunkhira kuti awonjezere kununkhira ndi kununkhira kwazinthu. Kachiwiri, mowa wa juniper umagwiritsidwanso ntchito ngati fungicide ndi kuteteza, ndipo nthawi zambiri amagwiritsidwa ntchito popanga mankhwala ophera tizilombo toyambitsa matenda ndi fungicides.

Pali njira zingapo zopangira juniperol. Nthawi zambiri, imatha kutulutsidwa ndi distillation yamafuta osasinthika kuchokera kumasamba a juniper kapena mbewu zina za cypress, kenako kupatulidwa ndikuyeretsedwa kuti mupeze juniperol. Mowa wa Hinoki ukhoza kupangidwanso ndi kaphatikizidwe ka mankhwala.

Chidziwitso chachitetezo cha juniperol: Sichiwopsezo chocheperako ndipo nthawi zambiri chimawonedwa ngati chotetezeka. Monga organic compound, imafunikabe kusamaliridwa ndikusungidwa bwino. Pewani kukhudza khungu ndi maso, ndipo muzimutsuka nthawi yomweyo ndi madzi ngati mwakumana mwangozi. Iyenera kusungidwa kutali ndi moto wotseguka ndi kutentha kwambiri, ndikusungidwa pamalo ozizira, owuma.

Zam'mbuyo: Z-ASP-OBZL (CAS# 4779-31-1)

Ena: 3-(Trifluoromethoxy) benzyl bromide (CAS# 50824-05-0)

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