1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenylpiperazine CAS 61337-89-1

1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenylpiperazine CAS 61337-89-1 kuyambitsa

Zakuthupi
Mawonekedwe: Pansi pazikhalidwe zowoneka bwino, imatha kukhala yolimba kwambiri, koma mawonekedwe a kristalo, mtundu ndi zina ziyenera kuphatikizidwa ndi kuwunika kwaukadaulo wama microscope ndi zolemba zolemba kuti zifotokoze bwino. Maonekedwe olimba amatsimikizira momwe zimagwirira ntchito panthawi yosungira, zoyendetsa ndi kupeza, mwachitsanzo, zolimba za crystalline ndizoyenera kugwiritsidwa ntchito ndi spatula.
Kusungunuka: Pazosungunulira organic, monga ethanol ndi methylene chloride, zitha kuwonetsa mosiyanasiyana kusungunuka. The solubility deta mu zosungunulira organic ndi wofunika kwambiri kwa organic kaphatikizidwe zatsopano ntchito monga zopangira kapena wapakatikati, kuti asayansi akhoza zenera zoyenera anachita zosungunulira kachitidwe kuonetsetsa kuti anachita ikuchitika uniformly ndi efficiently.

Synthesis njira
Pyridine ndi zotumphukira za piperazine zimagwiritsidwa ntchito ngati zida zoyambira, ndipo machitidwe akale achilengedwe monga nucleophilic substitution ndi condensation amagwiritsidwa ntchito popanga ma cell frameworks. Mwachitsanzo, zotumphukira za pyridine zokhala ndi chitetezo chamagulu ogwirira ntchito zimayamba kukumana ndi nucleophilic substitution reaction ndi activated piperazine precursors pansi pamikhalidwe yamchere kuti apange mafungulo oyambira; Pambuyo pake, mutatha kusankha njira zodzitetezera ndi hydroxymethylation, zomwe mukufuna zitha kupezeka. Lonse kaphatikizidwe ndondomeko amafuna okhwima kulamulira anachita kutentha, anachita nthawi ndi chiŵerengero cha zinthu, ndi kupatuka pang'ono adzakhala amapeza zonyansa, zimakhudza chiyero ndi zokolola za mankhwala.

ntchito
Mankhwala R & D: Mapangidwe ake apadera a maselo amagwirizanitsa magulu ogwira ntchito monga pyridine ndi piperazine, kusonyeza makhalidwe omwe angakhale mankhwala otsogolera mankhwala. Maguluwa amatha kuyanjana makamaka ndi mapuloteni omwe amawatsata, monga ma neurotransmitter receptors, m'zamoyo, kupereka ma tempuleti atsopano opangira mankhwala opangira mankhwala ochizira matenda amisala ndi matenda amisala. Ofufuza asintha mawonekedwe ake ndikuyesa ntchito yake kuti afufuze mosalekeza kuthekera kwake kwamankhwala.
Zomangamanga Zomangamanga: Pakuphatikiza kwathunthu kwa mamolekyu ovuta, ndi chomangira chapamwamba kwambiri. Akatswiri a zamankhwala amatha kugwiritsa ntchito malo awo omwe akugwira ntchito kuti agwirizane ndi magulu osiyanasiyana ogwira ntchito kuti awonjezere unyolo wa carbon carbon ndikupanga makina amitundu yambiri, kutsegulira malingaliro ophatikizika ndi malo ogwirira ntchito kuti apange ma organic compounds okhala ndi zolemba zatsopano komanso ntchito zapadera.