1H-Pyrazole-3-carboxylicacid 5-methyl-(CAS# 696-22-0)
| Zizindikiro Zowopsa | Xi - Zosangalatsa |
| Zizindikiro Zowopsa | R36/37/38 - Zokwiyitsa maso, kupuma komanso khungu. |
| Kufotokozera Zachitetezo | S26 - Mukakhudza maso, yambani nthawi yomweyo ndi madzi ambiri ndikupempha uphungu wachipatala. S37/39 - Valani magolovesi oyenera komanso chitetezo chamaso / kumaso |
Mawu Oyamba
Ndi organic pawiri ndi mankhwala chilinganizo C5H5N2O2. Nthawi zambiri imakhala yopanda mtundu mpaka yotumbululuka yachikasu yolimba.
Pawiri ali magulu awiri zinchito, mmodzi ndi pyrazole mphete ndi ena ndi carboxylic acid zinchito gulu. Lili ndi kusungunuka kwapakatikati ndipo limasungunuka m'madzi ndi zosungunulira wamba. Gulu la methyl mu kapangidwe kake limapangitsa kukhala hydrophobic.
Monga heterocyclic pawiri, 5-methyl-ali ndi zosiyanasiyana zochita zamoyo. Amagwiritsidwa ntchito kwambiri pofufuza zamankhwala ndi kaphatikizidwe ka mankhwala, nthawi zambiri ngati zopangira kapena zapakatikati. Zomwe zimagwiritsidwa ntchito mwapadera zimaphatikizapo kaphatikizidwe ka ma analogi a vitamini B1, mankhwala ophera tizilombo, ma plavix inhibitors (mankhwala omwe amagwiritsidwa ntchito poletsa kukula kwa mbewu), ndi zina zotero.
Kukonzekera, 5-methyl-ikhoza kupezedwa pochita atomu ya nayitrogeni ya mphete ya pyrazole ndi methylating agent (mwachitsanzo methyl iodide). Njirayi imayendetsedwa ndi N-methylation reaction, njira yodziwika bwino yomwe imatengera nucleophile yogwirizana ndi N-methyl reagent.
