1H-Pyrrolo[2 3-b]pyridine 6-methoxy-(CAS# 896722-53-5)

Mawu Oyamba

6-methoxy-1H-cryrolo [2,3-b]pyridine ndi organic pawiri ndi mankhwala formula C9H8N2O. Makhalidwe ake ndi awa:

1. Maonekedwe: 6-methoxy-1H-chrrolo [2,3-b]pyridine ndi yopanda mtundu mpaka kristalo wachikasu.

2. malo osungunuka: pafupifupi 105-108 ℃.

3. Powira: pafupifupi 325 ℃.

4. Kusungunuka: Kusungunuka mu zosungunulira za organic monga chloroform, methanol ndi dimethyl sulfoxide, komanso kusungunuka pang'ono m'madzi.

6-methoxy-1H-yrrolo [2,3-b]pyridine ali ndi ntchito zofunika pa kafukufuku wamankhwala ndi mankhwala, monga:

1. Chithandizo cha mankhwala: Amagwiritsidwa ntchito kwambiri pofufuza ndi chitukuko cha anti-tumor, anti-inflammatory, anti-cancer ndi mankhwala ena.

2. Kaphatikizidwe ka Chemical: Monga chofunikira chapakati pakupanga organic, itha kugwiritsidwa ntchito popanga zovuta zamagulu azinthu.

Njira zokonzekera 6-methoxy-1H-cryrolo [2,3-b]pyridine makamaka ndi izi:

1. N-methylation reaction ya indole: Indole imakhudzidwa ndi methyl halide kuti ipange 6-methyl indole, ndiyeno imachita ndi N-methyl vinyl amine kuti ipange 6-methoxy-1H-cryrolo [2,3-b] pyridine.

2. Redox reaction of indole: 6-methoxy-1H-pyridolo [2,3-b] pyridine ingapezeke pochita indole ndi sodium nitrite ndi tert-butyl peroxide.

Ponena za chidziwitso cha chitetezo, pali maphunziro ochepa pa kawopsedwe ndi kuopsa kwa 6-methoxy-1H-pyridolo [2,3-b]pyridine, kotero kuwunika kwapadera kwa chitetezo kumafunikira kufufuza kwina. Mukamayesa kapena kugwiritsa ntchito, njira zoyeserera zolondola ziyenera kutsatiridwa, kupewa kukhudzana mwachindunji ndi khungu ndi maso, samalani zodzitetezera, ndipo pewani kutulutsa ma aerosols kapena fumbi. Ngati ndi kotheka, iyenera kugwiritsidwa ntchito pamalo abwino mpweya wabwino.