2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine(CAS#865363-93-5)
Kuyambitsa 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine (CAS:865363-93-5), analogi yochititsa chidwi ya nucleoside yomwe yakhazikitsidwa kuti isinthe gawo la biology ya maselo ndi kafukufuku wamankhwala. Kapangidwe katsopano kameneka kapangidwa kuti kamathandizira kumvetsetsa kwa ma nucleic acid ndi njira zama cell, ndikupangitsa kuti ikhale chida chamtengo wapatali kwa ofufuza ndi asayansi.
2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine imadziwika ndi kusintha kwapadera kwapangidwe, komwe kumaphatikizapo kusintha kwa ethynyl ndi fluorine pa malo a 4 ndi 2, motero. Zosinthazi sizimangowonjezera kukhazikika komanso kupezeka kwa bioavailability komanso kumapangitsanso kuthekera kwake kulowa mu nembanemba zam'manja, zomwe zimapangitsa kuti pakhale kutulutsa kogwira mtima komanso kutengeka m'magulu osiyanasiyana achilengedwe.
Analogi ya nucleoside iyi yawonetsa kuthekera kodalirika muzogwiritsa ntchito zosiyanasiyana, kuphatikiza kafukufuku wa antiviral ndi anticancer. Kutha kwake kutsanzira ma nucleosides achilengedwe pomwe ikuwonetsa mawonekedwe apadera amthupi kumapangitsa kuti ikhale yoyenera pakupanga zida zatsopano zochizira. Ofufuza angagwiritse ntchito 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine kuti aphunzire RNA ndi DNA synthesis, kufufuza momwe ma enzyme amagwirira ntchito, ndi kufufuza njira zogwiritsira ntchito mankhwala omwe alipo.
Kuphatikiza pa ntchito zake zofufuzira, chigawochi chilinso chokonzeka kuchitapo kanthu pakupanga chithandizo cham'badwo wotsatira. Popereka zidziwitso za khalidwe la nucleic acid ndi machitidwe, 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine ingathandize pakupanga mankhwala othandiza komanso okhudzidwa ndi matenda osiyanasiyana.
Mwachidule, 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine (CAS:865363-93-5) ndi analogi wanthawi zonse wa nucleoside yemwe amapereka mwayi wosayerekezeka wa kafukufuku ndi chitukuko cha mamolekyulu a biology ndi pharmacology. Landirani tsogolo la zopezeka zasayansi ndi gulu lapaderali ndikutsegula mwayi watsopano muzofufuza zanu.
