4- [(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile(CAS# 189956-45-4)

Molecular Formula	Chithunzi cha C11H8N4O
Molar Misa	212.21
Kuchulukana	1.31±0.1 g/cm3(Zonenedweratu)
Melting Point	>300°C
Boling Point	399.7 ° C pa 760 mmHg
Pophulikira	195.6°C
Kusungunuka	DMSO (Pang'ono), Methanol (Pang'ono)
Kuthamanga kwa Vapor	0-0Pa pa 20-25 ℃
Maonekedwe	Zolimba
Mtundu	Pale Brown kupita ku Brown
pKa	8.66±0.40 (Zonenedweratu)
Mkhalidwe Wosungira	2-8 ° C
Refractive Index	1.67

Tsatanetsatane wa Zamalonda

LogP	0.9 pa pH6.6
ntchito	4 - [(4-hydroxy-2-pyrimidinyl) amino] benzonitrile angagwiritsidwe ntchito ngati wapakatikati mu kaphatikizidwe organic ndi mankhwala wapakatikati, ndipo angagwiritsidwe ntchito mu labotale Organic kaphatikizidwe ndondomeko ndi mankhwala ndi mankhwala kafukufuku ndi chitukuko ndondomeko.
kukonzekera	kuyeza 2-(methylthio) pyrimidine -4(3H) -imodzi (3g,21mmol) ndi 4-aminobenzonitrile (2.99g,25mmol) mu botolo la pansi la 50mL, lotetezedwa ndi nayitrogeni, kutenthedwa pang'onopang'ono mpaka 180 ℃, ndikuchitapo 8. maola. Zomwezo zitakhazikika, 20mL ya acetonitrile imawonjezedwa kwa akupanga chithandizo, kusefera, keke ya fyuluta imatsukidwa ndi acetonitrile, palibe zotsalira za 4-aminobenzonitrile zomwe zimadziwika ndi TLC, ndipo kuwala kwachikasu kolimba komwe kumapezeka mwa kuyanika keke ya fyuluta ndi 4-( (4-oxo -1, 6-dihydropyrimidine -2-yl) amino) benzonitrile ndi zokolola za 73.6%.