5-Trifluoromethyl-pyridine-2-carboxylic acidmethyl ester (CAS# 124236-37-9)

Methyl 5-trifluoromethylpyridine-2-carboxylate, yemwenso amadziwika kuti TFP ester, ndi organic pawiri. Zotsatirazi ndizofotokozera za chikhalidwe chake, kagwiritsidwe ntchito, kapangidwe ndi chitetezo:

Chilengedwe:
-Maonekedwe: madzi opanda mtundu
-Chilinganizo cha maselo: C8H4F3NO2
-Kulemera kwa maselo: 205.12g / mol
-Kuchulukana: 1.374 g/mL
-Kuwira: 164-165°C

Gwiritsani ntchito:
- TFP esters amagwiritsidwa ntchito kwambiri mu kaphatikizidwe ka organic ndi kafukufuku wamankhwala. Ndiwothandiza onunkhira gulu kuteteza reagent, amene angagwiritsidwe ntchito kuteteza amino gulu, hydroxyl gulu ndi gulu thioether.
-Itha kugwiritsidwa ntchito ngati mankhwala apakatikati pakupanga mankhwala achilengedwe okhala ndi magulu a trifluoromethyl.
-Kuonjezera apo, TFP ester ingagwiritsidwenso ntchito popanga mankhwala a amide, ndipo imagwiritsidwa ntchito kwambiri mu kafukufuku wa mankhwala, mankhwala ndi mankhwala ophera tizilombo toyambitsa matenda a ester kusinthana ndi chitetezo cha amino.

Njira Yokonzekera:
- TFP esters ikhoza kukonzedwa pochita trifluoromethylpyridine ndi methyl 2-formate. Zomwe zimachitika nthawi zambiri zimachitika kutentha ndipo zomwe mukufuna zimatha kuyeretsedwa ndi distillation.

Zambiri Zachitetezo:
- TFP ester imatengedwa kuti ndi yotetezeka pansi pazikhalidwe zogwiritsidwa ntchito. Komabe, monga organic pawiri, ali ndi ngozi kuthekera.
-Kukhudza khungu ndi maso mwachindunji kungayambitse mkwiyo kapena kuvulala. Chifukwa chake, ndikofunikira kuvala zida zoyenera zodzitetezera monga magolovesi ndi magalasi mukamagwiritsa ntchito.
-Kuonjezera apo, TFP ester iyeneranso kusungidwa kutali ndi moto ndi kutentha kwakukulu kuti zisawonongeke moto kapena kuphulika.

Kuti mudziwe zambiri za kagwiritsidwe ntchito ndi chitetezo, chonde funsani mabuku okhudzana ndi mankhwala kapena funsani katswiri.