ALPHA-ISO-METHYLIONONE(CAS#127-51-5)
| Zizindikiro Zowopsa | Xi - Zosangalatsa |
| Zizindikiro Zowopsa | 43 - Itha kuyambitsa chidwi pakukhudzana ndi khungu |
| Kufotokozera Zachitetezo | S24/25 - Pewani kukhudzana ndi khungu ndi maso. S36/37 - Valani zovala zoyenera zodzitchinjiriza ndi magolovesi. |
| Ma ID a UN | UN1230 - kalasi 3 - PG 2 - Methanol, yankho |
| WGK Germany | 2 |
| Poizoni | GRAS (FEMA). |
Mawu Oyamba
dziwitsani
Kusakaniza kwa methyl ndi ethyl isomethyl violet ketone ndi methyl ndi ethyl ortho methyl violet ketone.
chilengedwe
Alpha isomethylprednisolone ndi organic pawiri. Ndi mtundu wofiirira wa crystalline wolimba. Kutentha, kumakhala ndi fungo lapadera.
Alpha isomethylprednisolone ndi ketone yonunkhira. Amachokera ku methylation reaction ya violet alcohol ndipo amatchedwa isomethyl violet ketone. Mapangidwe ake a maselo amakhala ndi mphete yonunkhira komanso gulu la ketone.
Pa kutentha, zimakhala zolimba, koma zimatha kusungunuka ndi kutentha. Sipasungunuke m'madzi, koma imatha kusungunuka m'madzi ena monga ethanol ndi dichloromethane. Imakhudzidwa ndi kuwala ndipo imatha kukumana ndi photolysis reaction pansi pa kuwala kwa ultraviolet.
Pankhani ya mankhwala, α - isomethylprednisolone ndi mankhwala othandizira. Imatha kukumana ndi zochitika monga makutidwe ndi okosijeni, kuchepetsa, kuwonjezera, ndikusintha. Imakhudzidwa ndi ma electrophilic reagents kupanga zinthu zowonjezera. Ikhoza kukhala protonated pamaso pa amphamvu zidulo. Itha kusinthidwanso kukhala ma ketone acid kudzera muzochita zamakutidwe ndi okosijeni.
Njira yopangira
Zotsatirazi ndi njira yodziwika bwino yopangira alpha isomethylprednisolone:
Kukonzekera kwazinthu zoyambira: Konzani zida zoyambira, kuphatikiza Isobutyl ketone ndi Cyclohexanone. Mankhwala awiriwa ndi otsogolera ofunikira pa kaphatikizidwe ka α - isomethylprednisolone.
Kukonzekera kochitika: Reactte isodecanone ndi cyclohexanol pansi pamikhalidwe yoyenera. Zomwe zimachitika kawirikawiri ndikuchita zomwe zimachitika pansi pa acidic, ndipo zomwe zimagwiritsidwa ntchito nthawi zambiri zimakhala ndi sulfuric acid (H2SO4) ndi phosphoric acid (H3PO4).
Zochita: Sakanizani kuchuluka kwa isodecanone ndi cyclohexanol, ndikuwonjezera chothandizira asidi. Kenako, zomwe zimachitikazo zimachitika pa kutentha koyenera, komwe kumagwiritsidwa ntchito nthawi zambiri kutentha kwa 50-70 digiri Celsius. Zomwe zimachitika nthawi zambiri zimakhala maola angapo mpaka makumi a maora.
Kupatukana ndi kuyeretsedwa: Zomwe zimachitikazo zikatha, mankhwalawa amayeretsedwa kusakanizana ndi distillation kapena njira zina zolekanitsa.
Crystallization ndi kuyanika: Crystallize ndi kupukuta mankhwala oyeretsedwa kuti mupeze chomaliza cha alpha isomethylprednisolone.
