Boc-Asp-OtBu (CAS# 34582-32-6)

Mawu Oyamba

Boc-Asp-OtBu, yomwe imadziwika kuti Boc-Asp-OtBu, ndi organic pawiri. Zotsatirazi ndikuyambitsa zina mwazinthu zake, kagwiritsidwe ntchito, kapangidwe kake ndi zambiri zachitetezo:

Chilengedwe:

-Maonekedwe: Zinthu zopanda mtundu za crystalline kapena zaufa.

-Chilinganizo cha maselo: C≡H≡NO-7.

-Kulemera kwa maselo: 393.47g / mol.

- Malo osungunuka: pafupifupi 68-70 ° C.

-Kusungunuka: Kusungunuka muzinthu zina zosungunulira, monga dimethylformamide (DMF) ndi dichloromethane (DCM).

Gwiritsani ntchito:

- Boc-Asp-OtBu ndi gulu lomwe limagwiritsidwa ntchito poteteza, lomwe nthawi zambiri limagwiritsidwa ntchito popanga ma peptides ndi mapuloteni. Itha kuteteza magulu a carboxyl ndi amino a glutamic acid (Asp) ndikuletsa zochitika mwangozi ndi kuwonongeka.

- Boc-Asp-OtBu itha kugwiritsidwanso ntchito ngati njira zolumikizirana ndi organic synthesis, monga kaphatikizidwe ka peptide ndi kaphatikizidwe ka mankhwala.

Njira Yokonzekera:

-Kawirikawiri, Boc-Asp-OtBu imakonzedwa pochita mogwirizana ndi amino acid (L-glutamic acid) ndi gulu loteteza tert-butyl (Boc) ndi gulu loteteza tert-butoxycarbonyl (OtBu). Zomwe zimachitikazi zimachitika pamikhalidwe yoyenera, mwachitsanzo powonjezera cholumikizira monga 1-(trimethylsilyl) -1H-pyrazol-3-one (TBTU) kapena N,N'-disopropylmethylamide (DIPCDI) mu zosungunulira organic.

Zambiri Zachitetezo:

- Boc-Asp-OtBu yokhala ndi kawopsedwe kochepa.

-Popeza ndi organic compound, pewani kutulutsa fumbi kapena kukhudzana ndi khungu ndi maso.

-Pogwira ntchito, muyenera kutsatira njira zoyenera zotetezera ma labotale, monga kuvala magolovesi oteteza komanso kuteteza maso.

-Posunga, iyenera kusungidwa pamalo ozizira, owuma, komanso kutali ndi moto ndi oxidizing agents.

Zomwe zili pamwambazi ndizongogwiritsa ntchito, chonde tsatirani zoyeserera zoyeserera zamankhwala mukamagwiritsa ntchito Boc-Asp-OtBu.