BOC-D-2-Amino butyric acid (CAS# 45121-22-0)

Mawu Oyamba

Boc-D-Abu-OH(Boc-D-Abu-OH) ndi organic pawiri ndi izi:

1. maonekedwe ndi katundu: chikhalidwe wamba thupi ndi woyera galasi kapena crystalline ufa.

2 mankhwala katundu: ndi mtundu wa mankhwala amide, ali solubility wabwino, mu zosungunulira organic (monga dimethyl sulfoxide, dichloromethane, acetone, etc.) mu solubility mkulu.

3. Kukhazikika: kukhazikika pansi pazikhalidwe zambiri, koma kukhudzana ndi ma okosijeni amphamvu ndi kutentha kwakukulu kuyenera kupewedwa.

Ntchito za Boc-D-Abu-OH zimakhazikika kwambiri pankhani ya kaphatikizidwe ka organic, komwe amagwiritsidwa ntchito kwambiri pofufuza zamankhwala ndi biochemistry, ntchito zina zikuphatikiza:

1. kaphatikizidwe ka peptide: monga gulu loteteza, litha kukhala mu kaphatikizidwe ka peptide kuti muteteze gulu la amine, kuti lipewe kuchitapo kanthu kosagwirizana.

2. kaphatikizidwe ka mankhwala: angagwiritsidwe ntchito ngati wapakatikati pokonzekera mamolekyu amphamvu a mankhwala ndi mankhwala omwe amaphatikiza mankhwala.

3. Maphunziro a Biological Active: Zochokera ku Boc-D-Abu-OH zitha kugwiritsidwa ntchito poyesa zochitika zamoyo ndi mankhwala a pharmacokinetic azinthu zina.

Njira yokonzekera Boc-D-Abu-OH nthawi zambiri imatheka ndi izi:

1. Gwiritsani ntchito ma reagents oyenerera kuti mutembenuzire methyl propionate mu dimethyl sulfoxide kukhala N-BOC-alanine methyl ester.

2. N-BOC-alanine methyl ester imapangidwanso ndi hydrolyzed pansi pa zinthu zamchere kuti apange Boc-D-Abu-OH.

Ponena za chitetezo cha Boc-D-Abu-OH, mfundo zotsatirazi ziyenera kudziwidwa:

1. Poganizira kuti ndi mankhwala, iyenera kugwiridwa ndi kusungidwa bwino, kupewa kukhudzana ndi khungu ndi maso, komanso kupewa moto.

2. mu ntchito ayenera kutsatira njira zasayansi chitetezo.

3. Kuti muwunikire chitetezo cha mankhwala, mapepala okhudzana ndi chitetezo ndi zolemba ziyenera kufufuzidwa kuti zitsimikizidwe kuti zikugwiritsidwa ntchito moyenera komanso motetezeka.