BOC-D-ASP(OBZL)-OH(CAS# 92828-64-3)

Mawu Oyamba

(3R) -4-(benzyloxy) -3 - [(tert-butoxycarbonyl)amino] -4-oxobutanoic acid (dzina losakondedwa)((3R) -4-(benzyloxy) -3- [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid) ndi organic pawiri omwe mamolekyulu ake ndi C16H21NO6.

Pawiriyi ndi yochokera ku aspartic acid yokhala ndi zotsatirazi:

-Maonekedwe ndi woyera crystalline ufa;

-Wokhazikika kutentha, koma amawola pa kutentha kwakukulu;

-Kusungunuka mu zosungunulira za organic monga methanol, ethanol ndi dichloromethane.

(3R) -4-(benzyloxy) -3 - [(tert-butoxycarbonyl)amino] -4-oxobutanoic acid (dzina losasankhidwa) ali ndi ntchito zambiri pazamankhwala:

-Izo ntchito ngati wapakatikati kwa synthesis wa polypeptides ndi mankhwala ndi aspartic asidi zotsalira mu mapuloteni;

-Itha kugwiritsidwanso ntchito ngati chopangira chapakatikati chamankhwala.

Mu labotale, njira yokonzekera (3R) -4-(benzyloxy) -3--[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (dzina losakondedwa) nthawi zambiri imakhala pochita gulu la carboxyl la aspartic acid ndi tert-butoxycarbonyl isocyanate, ndikuyambitsa magulu a benzyl ester kudzera muzochita zoyenera.

Ponena za chitetezo, (3R) -4-(benzyloxy) -3-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (dzina losasankhidwa) ali ndi kawopsedwe kochepa komanso ngozi zambiri, motero ntchito yake yotetezeka iyenera kutsata labotale yodziwika bwino. malangizo otetezeka. Valani zida zodzitetezera zoyenera monga magalasi, magolovesi ndi malaya a labotale mukamagwiritsa ntchito kapena pogwira. Pa nthawi yomweyo, kupewa kukhudzana ndi amphamvu oxidants ndi combustibles.