BOC-GLY-GLY-GLY-OH (CAS# 28320-73-2)

Mawu Oyamba

Tert-Butoxycarbonylglycyl glycylglycine (Boc-Gly-Gly-Gly-OH) ndi organic pawiri yokhala ndi izi:

Chilengedwe:

-Maonekedwe: nthawi zambiri kristalo woyera kapena ufa wa crystalline

-Chilinganizo cha maselo: C17H30N4O7

-Kulemera kwa maselo: 402.44g / mol

- Malo osungunuka: pafupifupi 130-132 ° C

-Kusungunuka: Kusungunuka mu zosungunulira za organic monga dimethylformamide (DMF), dichloromethane, chloroform, ndi zina, zosasungunuka m'madzi.

Gwiritsani ntchito:

Boc-Gly-Gly-Gly-OH amagwiritsidwa ntchito kwambiri popanga organic synthesis, makamaka ngati kuteteza magulu kapena magulu. Itha kugwiritsidwa ntchito ngati gulu loteteza la ma amino acid kuti lipewe zochitika zina, ndipo limagwiritsidwa ntchito popanga gawo lolimba, kaphatikizidwe ka peptide ndi kaphatikizidwe ka mankhwala.

Njira:

Njira yodziwika bwino yokonzekera Boc-Gly-Gly-Gly-OH ndiyo kuyambitsa gulu loteteza la tert-butoxycarbonyl pagulu la carboxyl la glycine. Zina mwazinthu izi:

1. Glycine imakhudzidwa ndi kusakaniza kwa sodium nitrite ndi sulfuric acid kuti ipeze tert-butoxycarbonyl glycinate.

2. Gulu loteteza Ester limachotsedwa ndi hydrolysis reaction kuti ipeze Boc-glycine.

3. Bwerezani masitepe omwe ali pamwambawa kawiri kuti mulowetse gulu la carboxyl la glycine m'magulu awiri oteteza tert-butoxycarbonyl motsatana kuti mupeze Boc-Gly-Gly-Gly-OH.

Zambiri Zachitetezo:

Kugwiritsa ntchito Boc-Gly-Gly-Gly-OH kuyenera kulabadira izi:

-Pewani kukhudzana ndi khungu ndi maso, chifukwa zingakhumudwitse khungu ndi maso.

-Valani magolovesi oteteza, magalasi ndi zovala zodzitchinjiriza mukamagwira ntchito.

-Kugwira ntchito pamalo olowera mpweya wabwino kuti asapume fumbi kapena nthunzi wake.

-zisungidwe kutali ndi moto, kutentha ndi okosijeni, sungani chidebe chosindikizidwa, kusungidwa pamalo ozizira, owuma.