BOC-L-Phenylglycine (CAS# 2900-27-8)
| Kufotokozera Zachitetezo | S22 - Osapumira fumbi. S24/25 - Pewani kukhudzana ndi khungu ndi maso. |
| WGK Germany | 3 |
| HS kodi | 2924 29 70 |
Mawu Oyamba
N-Boc-L-Phenylglycine ndi mankhwala opangidwa ndi organic omwe amapangidwa ndi kupanga mgwirizano wa mankhwala pakati pa amino gulu (NH2) la glycine ndi gulu la carboxyl (COOH) la benzoic acid. Mapangidwe ake ali ndi gulu loteteza (gulu la Boc), lomwe ndi gulu la tert-butoxycarbonyl, lomwe limagwiritsidwa ntchito kuteteza reactivity ya gulu la amino.
N-Boc-L-phenylglycine ili ndi zotsatirazi:
- Maonekedwe: Makristalo oyera olimba
- Kusungunuka: Kusungunuka mu zosungunulira za organic, monga dimethylformamide (DMF), dichloromethane, ndi zina zotero.
N-Boc-L-phenylglycine amagwiritsidwa ntchito popanga ma organic synthesis, makamaka popanga ma peptide. Gulu loteteza la Boc litha kutetezedwa ndi mikhalidwe ya acidic, kuti gulu la amino lizitha kuchitapo kanthu ndikuchita zotsatilapo. N-Boc-L-phenylglycine itha kugwiritsidwanso ntchito ngati chotuluka pomanga malo opangira ma peptide synthesis.
Kukonzekera kwa N-Boc-L-phenylglycine kumachitika makamaka ndi izi:
Glycine imapangidwa ndi benzoic acid kuti ipeze benzoic acid-glycinate ester.
Pogwiritsa ntchito lithiamu borotrimethyl ether (LiTMP) reaction, benzoic acid-glycinate ester idapangidwa ndi protonated ndikuchita ndi Boc-Cl (tert-butoxycarbonyl chloride) kuti ipeze N-Boc-L-phenylglycine.
- N-Boc-L-phenylglycine ikhoza kukhala yokhumudwitsa m'maso, pakhungu, ndi m'mapapo ndipo iyenera kupewedwa mukamagwiritsa ntchito.
- Zida zodzitetezera monga magolovesi a labotale, magalasi otetezera, ndi zina zotero ziyenera kuvala panthawi yogwira ntchito.
- Iyenera kuchitidwa pamalo olowera mpweya wabwino wa labotale.
- Pewani kukhudzana ndi ma oxidants ndi ma asidi amphamvu posunga.
- Ngati mwamezedwa kapena kupumitsidwa, funsani kuchipatala mwamsanga, bweretsani chidebe cha pawiri, ndipo perekani chidziwitso chofunikira cha chitetezo kwa dokotala.
