CBZ-D-ALLO-ILE-OH (CAS# 55723-45-0)

Mawu Oyamba

ZD-allo-Ile-OH . DCHA (ZD-allo-Ile-OH · DCHA) ndi organic compound ndi reagent kuteteza amino acid. Zotsatirazi ndizofotokozera za chikhalidwe chake, kagwiritsidwe ntchito, kapangidwe ndi chitetezo:

Chilengedwe:

-Chilinganizo chamankhwala: C23H31NO5

-Kulemera kwa maselo: 405.50g / mol

-Maonekedwe: Mwala wonyezimira woyera

-Posungunuka: 105-108°C

-Kusungunuka: Kusungunuka mu zosungunulira za organic monga acetone, ether, dichloromethane, osasungunuka m'madzi.

Gwiritsani ntchito:

- ZD-allo-Ile-OH . DCHA ndi reagent yomwe imagwiritsidwa ntchito kuteteza ma amino acid. Poyambitsa gulu la Cbz pa gulu la amino la amino acid, kusintha mwangozi kwa gulu la amino mu kaphatikizidwe ka mankhwala kungapewedwe.

-Nthawi zambiri amagwiritsidwa ntchito popanga peptide, makamaka pakuphatikizika kwa ma peptide okhala ndi mapangidwe apadera kapena zochitika.

Njira Yokonzekera:

- ZD-allo-Ile-OH. Kukonzekera kwa DCHA nthawi zambiri kumayamba kuchokera ku D-isoleucine, kenako imakumana ndi Cbz anhydride kuti esterification iwonetse gulu loteteza la Cbz. Pomaliza, DCHA (dichloroformic acid) imachitidwa ndi amino acid kupanga mchere wofanana.

Zambiri Zachitetezo:

- ZD-allo-Ile-OH . DCHA ilibe poizoni, koma iyenera kuchitidwa mosamala. Pewani kukhudza khungu ndi maso, valani magolovesi oteteza ndi magalasi ngati kuli kofunikira.

-Pakagwiritsidwe ntchito, njira zogwirira ntchito za labotale ziyenera kutsatiridwa komanso zida zoyenera zopumira mpweya ziyenera kugwiritsidwa ntchito.

-Posunga, sungani nkhokweyo pamalo owuma, ozizira kutali ndi komwe kungayatse moto ndi malawi otseguka.