Cbz-L-3-Cyclohexyl Alanine (CAS# 25341-42-8)
| WGK Germany | 3 |
Mawu Oyamba
Z-3-CYCLOHEXYL-L-ALANINE (Z-3-CYCLOHEXYL-L-ALANINE) ndi organic compound yokhala ndi zotsatirazi:
1. Maonekedwe: Makristali opanda mtundu kapena olimba.
2. Kusungunuka: mu zosungunulira zina za organic (monga dimethyl sulfoxide, methanol) zosungunuka, zosasungunuka m'madzi.
3. Malo osungunuka: pafupifupi 128-134 ℃.
4. Kapangidwe ka mankhwala: kapangidwe kake kamakhala ndi gulu la cyclic cyclohexane ndi unyolo wa α-amino acid.
Z-3-CYCLOHEXYL-L-ALANINE ali ndi ntchito zingapo ndikugwiritsa ntchito, kuphatikiza:
1. Kafukufuku wam'chilengedwe: ngati wapakatikati pakupanga ma peptides, mapuloteni kapena mankhwala osokoneza bongo.
2. Kukula kwa mankhwala: kungagwiritsidwe ntchito ngati chinthu chofufuzira cha mankhwala odana ndi chotupa, chifukwa cha dongosolo loperekera mankhwala.
3. Organic kaphatikizidwe: monga zofunika poyambira zinthu kaphatikizidwe wa organic mankhwala ndi mamangidwe enieni.
Njira yokonzekera Z-3-CYCLOHEXYL-L-ALANINE ili motere:
Pansi pa chitetezo cha nayitrogeni, L-cyclohexylalanine inasungunuka mu dimethyl sulfoxide, sodium p-trimethylmethane inawonjezeredwa kuti isungunuke, ndipo dibutylene carbonate ndi dihydroxy benzoin ketone (CbzCl) zinawonjezeredwa. Zomwe osakaniza amalimbikitsidwa firiji kwa nthawi, ndiye kuchepetsedwa ndi madzi, asidi ndi neutralized, crystallized, osambitsidwa ndi zouma kupereka mankhwala.
Pazambiri zachitetezo, palibe maphunziro a toxicological omwe adanenedwapo Z-3-CYCLOHEXYL-L-ALANINE. Machitidwe oyenerera a mu labotale, monga kuvala magolovesi a mu labotale ndi magalasi a mu labotale, ndi kugwira ntchito m’malo otuluka mpweya wabwino ayenera kugwiritsidwa ntchito pogwira ndi kugwiritsira ntchito chinthucho. Ngati mwakhudza khungu kapena maso mwangozi, muzimutsuka nthawi yomweyo ndi madzi ambiri ndikupempha thandizo lachipatala mwamsanga.
