clemastine fumarate(CAS#14976-57-9)
clemastine fumarate(CAS#14976-57-9)
Clementine Fumarate, nambala ya CAS 14976-57-9, ndi gulu lomwe likuyembekezeredwa kwambiri m'munda wa mankhwala.
Pankhani ya mankhwala, amapangidwa ndi zinthu zapadera zomwe zimaphatikizidwa molingana ndendende, ndipo kugwirizana kwa ma bond a mankhwala mkati mwa molekyulu kumatsimikizira kukhazikika kwake ndi reactivity. Maonekedwe nthawi zambiri ndi ufa woyera wa crystalline, womwe ndi wosavuta kusunga ndi kukonzekera mu mawonekedwe olimba. Pankhani ya solubility, imakhala ndi gawo lina la kusungunuka m'madzi, ndipo khalidweli limakhudzidwa ndi zinthu zachilengedwe monga kutentha ndi pH mtengo, zomwe zimakhudzanso kusankhidwa kwa mapangidwe mu chitukuko cha mankhwala, monga kulingalira kosiyana kwa chiwerengero cha kusungunuka popanga pakamwa. mapiritsi ndi syrup formulations.
Pankhani ya pharmacological zotsatira, Clementine Fumarate ndi wa gulu la antihistamines. Ikhoza kuletsa mpikisano wa histamine H1 receptor. Thupi likakumana ndi vuto ndipo kutulutsidwa kwa histamine kumayambitsa zizindikiro monga kuyetsemula, mphuno yothamanga, kuyabwa pakhungu, kufinya kwa maso, ndi zina zambiri, kumatha kuchepetsa kusapezakoko poletsa njira ya histamine mediated allergenic reaction. Amagwiritsidwa ntchito kwambiri pazachipatala pochiza matenda omwe sali odziwika bwino monga matupi awo sagwirizana rhinitis ndi urticaria, achepetsa kupsinjika kwa odwala ambiri.
Komabe, odwala ayenera kutsatira malangizo achipatala akamagwiritsa ntchito. Zomwe zimachitika nthawi zambiri monga kugona ndi kuuma kwapakamwa zimasiyana mosiyanasiyana chifukwa cha kusiyana kwa anthu. Madokotala ayenera kudziwa bwino mlingo ndi nthawi ya mankhwala malinga ndi msinkhu wa wodwalayo, thupi lake, kuopsa kwa matenda, ndi zina zotero, kuonetsetsa chitetezo cha mankhwala, kukulitsa mphamvu yake yotsutsa matupi awo sagwirizana, ndi kuthandiza odwala kuti achire. Ndi chitukuko chosalekeza cha kafukufuku wamankhwala, kuwunika tsatanetsatane wake komanso kuthekera kwa kuphatikiza mankhwala kumakulirakulira nthawi zonse.