D-1-N-Boc-prolinamide (CAS# 35150-07-3)

Mawu Oyamba

D-1-N-Boc-prolinamide(D-1-N-Boc-prolinamide) ndi organic pawiri yokhala ndi izi:

1. Maonekedwe: Makristalo oyera olimba.

2. chilinganizo cha maselo: C14H24N2O3.

3. Kulemera kwa maselo: 268.35g / mol.

4. malo osungunuka: pafupifupi 75-77 digiri Celsius.

5. Kusungunuka: Kusungunuka m'madzi ndi zosungunulira zina monga chloroform, ethanol ndi dimethyl sulfoxide.

Chimodzi mwazofunikira kwambiri za D-1-N-Boc-prolinamide ndi ngati chiral reagent for asymmetric synthesis in organic chemical synthesis. Itha kugwiritsidwa ntchito ngati chomangira cha mafupa a chiral kuti adziwitse zambiri zamatsenga kudzera m'malo ake amatsenga, potero kupeza mankhwala ophatikizika. Kuphatikiza apo, itha kugwiritsidwanso ntchito ngati njira yapakatikati yopangira mankhwala, mankhwala ophera tizilombo komanso mamolekyulu a bioactive.

Njira yokonzekera D-1-N-Boc-prolinamide nthawi zambiri imakhala yochitira N-Boc-L-proline ndi tert-butyl chloroformate pansi pamikhalidwe yamchere kuti ipange wapakatikati wa N-Boc-L-proline methyl ester, kenako kutentha kwa mankhwala kupanga zomwe mukufuna.

Pazambiri zachitetezo, maphunziro a toxicological mwatsatanetsatane akusowa D-1-N-Boc-prolinamide. Komabe, nthawi zambiri, ntchito zanthawi zonse zachitetezo cha labotale ziyenera kutsatiridwa, ndipo njira zodzitetezera monga magolovesi, magalasi ndi zovala zodzitchinjiriza ziyenera kutsatiridwa mukamagwiritsa ntchito. Kuonjezera apo, ziyenera kusungidwa mu chidebe chotsekedwa kuti zisagwirizane ndi mpweya ndi chinyezi. Ngati mwakoka mpweya mwangozi kapena kukhudza khungu ndi maso, muzimutsuka nthawi yomweyo ndi madzi ambiri ndikupempha thandizo lachipatala. Ngati zinyalala ziyenera kutayidwa, malamulo am'deralo ayenera kutsatiridwa. Ndikwabwino kugwiritsa ntchito ndikuwongolera pawiriyo motsogozedwa ndi munthu yemwe ali ndi luso laukadaulo.