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D-Glutamine (CAS # 5959-95-5) Chithunzi Chowonetsedwa
  • D-Glutamine (CAS# 5959-95-5) 1

D-Glutamine (CAS # 5959-95-5)

Chemical Property:

Molecular Formula C5 H10 N2 O3
Misa ya Molar 146.14
Kuchulukana 1.3394 (kuyerekeza movutikira)
Melting Point 184-185 ° C
Boling Point 265.74 ° C (kuyerekeza molakwika)
Kuzungulira Kwapadera (α) -32 º (589nm, c=10, N HCl)
Kusungunuka kwamadzi 42.53g/L(kutentha sikunatchulidwe)
Kusungunuka Zosungunuka m'madzi (9 mg/ml pa 25 °C), DMSO (<1 mg/ml pa 25 °C), ndi ethanol (<1 mg/m
Maonekedwe White crystalline ufa
Mtundu Choyera
Mtengo wa BRN 1723796
pKa 2.27±0.10 (Zonenedweratu)
Mkhalidwe Wosungira Khalani pamalo amdima, M'mlengalenga, Kutentha kwachipinda
Refractive Index -33 ° (C=5, 5mol/LH
MDL Mtengo wa MFCD00065607
Zakuthupi ndi Zamankhwala Malo osungunuka: 185
Maphunziro a in vitro Glutamine ndi ofunika kwambiri amino acid m'katikati mwa mitsempha ya mitsempha (CNS), yomwe imagwira ntchito yofunika kwambiri pa glutamate/GABA-Glutamine cycle (GGC). Mu GGC, Glutamine imasamutsidwa kuchoka ku astrocyte kupita ku ma neuron, komwe idzabwezeretsanso maiwe oletsa komanso osangalatsa a neurotransmitter. D-Glutamine yakhala ikugwiritsidwa ntchito pofufuza ntchito yake popereka chitetezo ku kusokonezeka kwa acetaldehyde-kuchititsa kusokoneza ntchito mu Caco-2 cell monolayer. Udindo wa L-Glutamine poteteza matumbo a epithelium ku kusokonezeka kwa acetaldehyde-omwe amalepheretsa ntchito yotchinga amawunikidwa mu Caco-2 cell monolayer. L-Glutamine inachepetsa kuchepa kwa acetaldehyde mu transepithelilal magetsi kukana ndi kuwonjezeka kwa permeability kwa inulin ndi lipopolysaccharide m'njira yodalira nthawi ndi mlingo; D-Glutamine, L-aspargine, L-arginine, L-lysine, kapena L-alanine sanapange chitetezo chachikulu. D-Glutamine imalepheranso kuwonetsa kuchepa kwa acetaldehyde mu TER ndikuwonjezera kutulutsa kwa inulin. D-Glutamine kapena glutaminase inhibitor mwa iwo okha sanakhudze TER kapena inulin flux mu ulamuliro kapena acetaldehyde-treated cell monolayers. Kupanda mphamvu kwa D-Glutamine poteteza ku acetaldehyde kukuwonetsa kuti chitetezo chothandizira L-Glutamine ndi chodziwika bwino.

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Zizindikiro Zowopsa Xi - Zosangalatsa
Zizindikiro Zowopsa 36/37/38 - Zokwiyitsa maso, kupuma komanso khungu.
Kufotokozera Zachitetezo S36/37/39 - Valani zovala zodzitchinjiriza zoyenera, magolovesi ndi chitetezo chamaso / kumaso.
S26 - Mukakhudza maso, yambani nthawi yomweyo ndi madzi ambiri ndikupempha uphungu wachipatala.
S27 - Chotsani nthawi yomweyo zovala zonse zowonongeka.
S24/25 - Pewani kukhudzana ndi khungu ndi maso.
WGK Germany 3
HS kodi 29241900

 

Mawu Oyamba

Isomero yosakhala yachilengedwe ya glutamine imakhala yosasungunuka mu methanol, ethanol, ether ndi benzene.

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