FMOC-D-Valine (CAS# 84624-17-9)
| Kufotokozera Zachitetezo | S22 - Osapumira fumbi. S24/25 - Pewani kukhudzana ndi khungu ndi maso. |
| WGK Germany | 3 |
| HS kodi | 2924 29 70 |
Mawu Oyamba
fmoc-D-valine(fmoc-D-valine) ndi reagent yamankhwala yomwe imagwiritsidwa ntchito makamaka mu kaphatikizidwe ka peptide ndi uinjiniya wa mapuloteni mu kaphatikizidwe kolimba. Lili ndi zotsatirazi:
1. mankhwala katundu: fmoc-D-valine ndi woyera olimba, ndi hydrophobic. Imasungunuka mu zosungunulira za organic monga dimethyl sulfoxide (DMSO) ndi methylene chloride, koma osasungunuka m'madzi. Maselo ake ndi C21H23NO5 ndipo kulemera kwake kwa maselo ndi 369.41.
2. gwiritsani ntchito: fmoc-D-valine ndi imodzi mwazinthu zofunika kwambiri pakupangira ma peptides ndi mapuloteni, angagwiritsidwe ntchito popanga ma peptides okhala ndi biologically. Amagwiritsidwa ntchito pophatikizira gawo lolimba kupanga unyolo wa peptide pogwiritsa ntchito ma condensation ndi zotsalira zina za amino acid. Kuphatikiza apo, itha kugwiritsidwanso ntchito pophunzira kaphatikizidwe ka peptides yogwira komanso kapangidwe ka mankhwala.
3. Njira yokonzekera: Kuphatikizika kwa fmoc-D-valine nthawi zambiri kumachitika ndi njira yopangira mankhwala. L-valine imayendetsedwa koyamba ndi gulu loteteza la Fmoc kuteteza gulu la amino muzochita za mankhwala. Gulu loteteza la Fmoc kenako limachotsedwa ndikuchitapo kanthu kuti lipereke fmoc-D-valine.
4. Chidziwitso chachitetezo: fmoc-D-valine ili ndi chitetezo chabwino nthawi zambiri imagwiritsidwa ntchito, komabe muyenera kulabadira zotsatirazi: kupewa kukhudzana ndi khungu ndi maso, monga kukhudzana mwangozi, muyenera kutsuka nthawi yomweyo ndi madzi ambiri, ndikupempha thandizo lachipatala; Pa opaleshoni ayenera kulabadira zakudya ndi ukhondo; zosungirako ziyenera kutsekedwa, kupewa kuwala kwa dzuwa ndi malo achinyezi. Mukamagwiritsa ntchito, chonde onani malangizo okhudzana ndi chitetezo ndi mapepala achitetezo azinthu (MSDS).
