Fmoc-DL-2-Aminobutyric acid (CAS# 174879-28-8)

Fmoc-DL-2-Aminobutyric acid (CAS# 174879-28-8) mawu oyamba

N-Fmoc-2-aminobutyric acid, yomwe imadziwikanso kuti N-(9-hemandryl) aminobutyric acid, ndi organic pawiri. Zotsatirazi zikufotokozera momwe zimakhalira, ntchito, njira zopangira ndi chidziwitso chachitetezo:

Ubwino:
N-Fmoc-2-aminobutyric acid ndi cholimba choyera mpaka chachikasu chokhala ndi zinthu zomwe zimasungunuka mosavuta mu zosungunulira za organic. Ndi mankhwala a acidic omwe amatha kupanga mchere ndipo ali ndi gulu loteteza phenyl (Fmoc) lomwe lingathe kuchotsedwa pansi pa acidic.

Gwiritsani ntchito:
N-Fmoc-2-aminobutyric acid imagwiritsidwa ntchito kwambiri popanga peptide mu kaphatikizidwe ka organic. Gulu lake loteteza phenyl lingateteze gulu la amino panthawi ya kaphatikizidwe kuti tipewe zochitika zina. Popanga peptide kaphatikizidwe, N-Fmoc-2-aminobutyric acid nthawi zambiri amagwiritsidwa ntchito ngati kaphatikizidwe wapakatikati pomanga unyolo wa peptide, ndipo pambuyo pa kaphatikizidwe, aminobutyric acid yomwe mukufuna ingapezeke pochotsa gulu loteteza phenyl.

Njira:
Kukonzekera kwa N-Fmoc-2-aminobutyric acid nthawi zambiri kumatheka poyambitsa gulu la phenyl-protecting (Fmoc) mu 2-aminobutyric acid. Masitepe enieni amakhudza kuchitapo kanthu kwa 2-aminobutyric acid ndi Fmoc-Cl (chloride ya gulu la Fmoc) muzosungunulira zoyenera kupanga N-Fmoc-2-aminobutyric acid, kenako ndikuchita sitepe yoyenera yoyeretsa kuti mupeze chinthu chomwe mukufuna.

Zambiri Zachitetezo:
N-Fmoc-2-aminobutyric acid ndi mankhwala omwe amafunikira kusamala pakagwiritsidwe ntchito. Zitha kukwiyitsa khungu, maso, ndi kupuma ndipo zimafunikira kuvala zida zoyenera zodzitetezera monga magolovesi, zovala zodzitchinjiriza, ndi zophimba nkhope pochita opaleshoni. Chophimbacho chiyenera kusungidwa ndikusamalidwa kutali ndi kuyatsa ndi kutentha kwakukulu kuti zisagwirizane ndi zoyaka. Pankhani yokhudzana ndi khungu kapena maso, muzimutsuka nthawi yomweyo ndi madzi ambiri ndikufunsana ndi dokotala.