Fmoc-L-Glutamic acid 1-tert-butyl ester (CAS# 84793-07-7)

Mawu Oyamba

Fluorene methoxycarbonyl-L-glutamate-1-tert-butyl ester, yomwe imadziwikanso kuti Fmoc-L-glutamic acid-1-tert-butyl ester, ndi organic pawiri yomwe imagwiritsidwa ntchito popanga peptide ndi kaphatikizidwe kolimba kaphatikizidwe ka organic.

Ubwino:

Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl ndi yolimba yokhala ndi makhiristo oyera mpaka achikasu. Lili ndi kusungunuka kochepa m'madzi koma kusungunuka kwabwino mu zosungunulira za organic monga dimethyl sulfoxide kapena methanol.

Gwiritsani ntchito:

Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl ndizomwe zimagwiritsidwa ntchito poteteza amino acid popanga peptide. Itha kugwiritsidwa ntchito kuteteza gululo kudzera mu zomwe zimachitika, kotero kuti iwululidwe mu kaphatikizidwe ndi kukulitsa unyolo wa peptide. Pagululi ndi loyenera makamaka pakupanga gawo lolimba, pomwe unyolo wa peptide umalumikizidwa ndi ma amino acid oteteza panthambi za utomoni.

Njira:

Kukonzekera kwa fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl nthawi zambiri kumatheka ndi kaphatikizidwe ka mankhwala. Fluorene methanol imayamba kupangidwa kukhala fluorene carboxyl chloride kudzera muzochita ndi mankhwala, kenako imachita ndi L-glutamic acid kupanga fluorene methoxycarbonyl-L-glutamic acid, ndipo pamapeto pake imachita ndi tert-butanol kupanga chomaliza.

Zambiri Zachitetezo:

Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl nthawi zambiri amawonedwa kuti alibe kawopsedwe wowonekera kwa anthu pansi pamikhalidwe yoyeserera. Njira zoyendetsera chitetezo cha labotale ziyenera kutsatiridwa pogwira, kuphatikiza kuvala magolovesi oteteza ndi magalasi, ndikugwira ntchito pamalo opumira bwino.