Fmoc-L-homophenylalanine (CAS# 132684-59-4)
Ngozi ndi Chitetezo
| Zizindikiro Zowopsa | Xi - Zosangalatsa |
| Zizindikiro Zowopsa | 36/37/38 - Zokwiyitsa maso, kupuma komanso khungu. |
| Kufotokozera Zachitetezo | S22 - Osapumira fumbi. S24/25 - Pewani kukhudzana ndi khungu ndi maso. S44 - S35 - Zinthu izi ndi chidebe chake ziyenera kutayidwa m'njira yotetezeka. S28 - Mukakhudza khungu, sambani nthawi yomweyo ndi sopo wambiri. S7 - Sungani chidebe chotsekedwa mwamphamvu. S4 - Khalani kutali ndi malo okhala. |
| WGK Germany | 3 |
| HS kodi | 2924 29 70 |
| Kalasi Yowopsa | ZOKWIYA |
Mawu Oyamba
2. Kusungunuka: Kusungunuka m'madzi osungunulira monga dimethyl sulfoxide (DMSO) ndi ethyl acetate (EtOAc), osasungunuka m'madzi.
3. chilinganizo cha maselo: C32H29NO4.
4. kulemera kwa maselo: 495.58.
Kugwiritsa ntchito kwakukulu kwa Fmoc-L-homophenylalanine ndi gulu loteteza mu kaphatikizidwe ka peptide. Fmoc ndi chidule cha furoyl ndi zotumphukira zake, zomwe zimatha kuteteza gulu la amino mu ma amino acid. Zikafunidwa kupanga unyolo wa peptide, gulu la amino litha kupezeka kuti lichitepo pochotsa gulu loteteza la Fmoc. Choncho, Fmoc-L-homophenylalanine imagwira ntchito yofunika kwambiri pokonzekera mankhwala a peptide ndi mamolekyu okhudzana ndi bioactive.
Njira yokonzekera Fmoc-L-homophenylalanine ndi yovuta kwambiri ndipo imaphatikizapo kaphatikizidwe kazinthu zambiri. Njira yokonzekera yodziwika bwino ndiyo kugwirizanitsa Fmoc-protected phenylalanine ndi ma reagents ena, monga silver azide formate (AgNO2), kutsatiridwa ndi mankhwala a trifluoroacetic acid kuti apereke Fmoc-L-homophenylalanine.
Mfundo zotsatirazi zachitetezo ziyenera kudziwidwa mukamagwiritsa ntchito Fmoc-L-homophenylalanine:
1. Pewani kukhudzana mwachindunji ndi khungu, maso ndi mucous nembanemba, chifukwa zikhoza kukwiyitsa thupi la munthu.
2. Kusungirako kuyenera kupewa kukhudzana ndi ma okosijeni amphamvu kapena ma asidi amphamvu kuti apewe zoopsa.
3. Gwiritsani ntchito zida zodzitetezera zoyenera monga magolovesi, magalasi oteteza komanso malaya a labotale mukamagwiritsa ntchito ndikugwira.
4. Ntchito zonse ziyenera kuchitika pansi pa mpweya wabwino wa labotale.
Mwachidule, Fmoc-L-homophenylalanine ndi gulu loteteza amino acid lomwe limagwiritsidwa ntchito popanga peptide synthesis ndipo limagwiritsidwa ntchito mosiyanasiyana. Pogwiritsira ntchito ndi kugwiritsira ntchito pawiri, m'pofunika kumvetsera kasamalidwe kotetezeka ndi kusunga.
