L-3-Aminoisobutyric acid (CAS# 4249-19-8)

Mawu Oyamba

Sb-aminoisobutyric acid (S-β-aminoisobutyric acid) ndi amino acid yokhala ndi mawonekedwe ake. Ndi amino acid osakhala achilengedwe okhala ndi mamolekyulu a C4H9NO2 ndi molekyulu yolemera 103.12g/mol.

Sb-aminoisobutyric acid ndi imodzi mwa ma stereoisomers awiri, ndipo kasinthidwe kake kamakhalabe mu mawonekedwe a L. Ndi woyera crystalline ufa, sungunuka m'madzi ndi mowa solvents. Pagululi ndi lokhazikika mumpweya koma limamva kutentha ndi kuwala.

Sb-aminoisobutyric acid ili ndi ntchito zambiri zofunika pathupi mu vivo, kuphatikiza mapuloteni kagayidwe, chitetezo chamthupi komanso chikoka pakugwira ntchito kwaubongo. Itha kugwiritsidwanso ntchito ngati chiral charged ndi fatty acid oxidase intracellular chonyamulira.

Sb-aminoisobutyric acid amagwiritsidwa ntchito makamaka m'munda wamankhwala pakupanga mankhwala, odana ndi khansa komanso kafukufuku wam'magazi. Angagwiritsidwe ntchito kuphunzira ntchito ya mapuloteni ndi michere, kapangidwe ka mapuloteni ndi nucleic zidulo, ndi lithe mankhwala, analgesics ndi zina bioactive mankhwala.

Njira zokonzekera Sb-aminoisobutyric acid zimatha kupangidwa kapena kuchotsedwa kuzinthu zachilengedwe. Njira imodzi yodziwika bwino yopangira ndi kutulutsa isovaleraldehyde. Kutulutsa kuchokera kuzinthu zachilengedwe nthawi zambiri kumachokera ku metabolites ya mabakiteriya ena kapena bowa.

Pazambiri zachitetezo, Sb-aminoisobutyric acid nthawi zambiri imadziwika kuti ndiyotetezeka pakagwiritsidwe ntchito m'mafakitale ndi ma labotale. Komabe, akadali mankhwala ndipo ayenera kutsata njira zoyenera zachitetezo cha labotale. Akakumana nacho, akuyenera kuchitapo kanthu zodzitetezera, kuphatikiza kuvala magolovesi, magalasi ndi zovala zodzitetezera. Ngati wakhudza kapena kumwa mowa mwangozi, chithandizo chamankhwala chiyenera kufunidwa mwamsanga.