Lacosamide (CAS# 175481-36-4)
Ngozi ndi Chitetezo
| Zizindikiro Zowopsa | R11 - Yoyaka Kwambiri R20/21/22 - Zowopsa pokoka mpweya, kukhudzana ndi khungu komanso kumeza. R36 - Zokhumudwitsa m'maso |
| Kufotokozera Zachitetezo | S16 - Khalani kutali ndi magwero oyatsira. S26 - Mukakhudza maso, yambani nthawi yomweyo ndi madzi ambiri ndikupempha uphungu wachipatala. S36/37 - Valani zovala zoyenera zodzitchinjiriza ndi magolovesi. |
| Ma ID a UN | UN 1648 3 / PGII |
| WGK Germany | 2 |
| HS kodi | 2924296000 |
Lacosamide (CAS # 175481-36-4) chiyambi
Lactamide ndi gulu la mankhwala omwe ali ndi mphete za lactam. Zotsatirazi ndizofotokozera za katundu, ntchito, njira zokonzekera ndi chidziwitso cha chitetezo cha laclamide:
Ubwino:
Makhalidwe a laclamide amadalira kapangidwe kake ka maselo ndi kukula kwa mphete. Kawirikawiri, lacamide ndi yoyera ya crystalline yolimba komanso yokhazikika. Ili ndi kusungunuka kwabwino, kusungunuka mu zosungunulira organic monga ethers ndi ketoni, komanso osasungunuka m'madzi.
Gwiritsani ntchito:
Laccamide ali ndi ntchito zosiyanasiyana m'makampani opanga mankhwala. Chofunika kwambiri mwa izi ndikugwiritsa ntchito ngati kalambulabwalo wa zinthu za polima. Mwachitsanzo, ulusi wa polyamide (nayiloni) amapangidwa ndi polymerizing laclamide. Laxamide itha kugwiritsidwanso ntchito ngati wapakatikati mu zosungunulira, zosungunulira, komanso ngati zopangira zopangira ulusi wopangira, mphira wopangira, mankhwala ndi utoto.
Njira:
Nthawi zambiri, kaphatikizidwe wa laxamide makamaka zimatheka ndi asidi-catalyzed cyclization. Makamaka, njira zokonzekera zomwe zimagwiritsidwa ntchito kwambiri ndi izi:
Njira ya pamine: imagwiritsa ntchito ma amines ndi asidi chloride kapena anhydride kuchitapo kanthu pamikhalidwe yoyenera kupanga laxamide.
Non-classical asidi catalytic njira: Mwachitsanzo, sing'anga mu chothandizira riyakitala wachiritsidwa kwathunthu, ferric kolorayidi ndi asidi chothandizira akhoza kusandulika laclamide pa kutentha otsika.
High-pressure reaction njira: Laclamine imapangidwa ndi chipangizo cha imimine ndi NBS pamalo opanikizika kwambiri.
Zambiri Zachitetezo:
Laxamide ndi mankhwala ndipo ayenera kusungidwa bwino pamalo owuma, ozizira, kutali ndi kumene kuli moto ndi okosijeni.
Panthawi yogwira ntchito, mpweya wabwino uyenera kusamalidwa ndipo zida zoyenera zodzitetezera monga magolovesi oteteza, zishango zakumaso, ndi zovala zoteteza maso ziyenera kugwiritsidwa ntchito.
Laclamide imatha kukwiyitsa khungu ndi maso.
Potaya zinyalala, ziyenera kutayidwa m’njira yoyenera mogwirizana ndi malamulo a m’deralo.
