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Levodopa (CAS# 59-92-7) Chithunzi Chowonetsedwa
  • Levodopa (CAS# 59-92-7) 1

Levodopa (CAS# 59-92-7)

Chemical Property:

Molecular Formula C9H11NO4
Misa ya Molar 197.19
Kuchulukana 1.3075 (kuyerekeza movutikira)
Melting Point 276-278 °C (kuyatsa)
Boling Point 334.28°C (kuyerekeza molakwika)
Kuzungulira Kwapadera (α) -11.7 º (c=5.3, 1N HCl)
Pophulikira 225 ° C
Kusungunuka kwamadzi Kusungunuka pang'ono m'madzi, kuchepetsa hydrochloric acid ndi formic acid. Zosasungunuka mu ethanol.
Kusungunuka Amasungunuka mosavuta mu dilute hydrochloric acid ndi formic acid, sungunuka m'madzi, osasungunuka mu ethanol, benzene, chloroform ndi ethyl acetate
Kuthamanga kwa Vapor 7.97E-09mmHg pa 25°C
Maonekedwe Ufa woyera wa crystalline woyera mpaka wamkaka
Mtundu Zoyera mpaka zotsekemera
Merck 14,5464
Mtengo wa BRN 2215169
pKa 2.32 (pa 25 ℃)
Mkhalidwe Wosungira 2-8 ° C
Kukhazikika Wokhazikika. Zosagwirizana ndi ma oxidizing amphamvu. Kuwala ndi mpweya.
Zomverera Simamva kuwala ndi mpweya
Refractive Index -12 ° (C = 5, 1mol/LH
MDL Mtengo wa MFCD00002598
Zakuthupi ndi Zamankhwala malo osungunuka 295 ° C
kusinthasintha kwapadera kwa kuwala -11.7 ° (c = 5.3, 1N HCl)
Gwiritsani ntchito Mankhwala othandiza pochiza ziwalo za mantha, makamaka ntchito Parkinson syndrome, etc

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Zizindikiro Zowopsa Xn - Zowopsa
Zizindikiro Zowopsa R22 - Zowopsa ngati zitamezedwa
R36/37/38 - Zokwiyitsa maso, kupuma komanso khungu.
R20/21/22 - Zowopsa pokoka mpweya, kukhudzana ndi khungu komanso kumeza.
Kufotokozera Zachitetezo S26 - Mukakhudza maso, yambani nthawi yomweyo ndi madzi ambiri ndikupempha uphungu wachipatala.
S36 - Valani zovala zoyenera zodzitetezera.
S24/25 - Pewani kukhudzana ndi khungu ndi maso.
WGK Germany 3
Mtengo wa RTECS AY5600000
FLUKA BRAND F CODES 10-23
TSCA Inde
HS kodi 29225090
Poizoni LD50 mu mbewa (mg/kg): 3650 ±327 pakamwa, 1140 ±66 ip, 450 ± 42 iv,> 400 sc; makoswe amuna, akazi (mg/kg):>3000,>3000 pakamwa; 624, 663 ip; >1500,>1500 sc (Clark)

 

Mawu Oyamba

Pharmacological zotsatira: odana ndi kugwedeza ziwalo mankhwala. Imalowa mu minofu yaubongo kudzera mu chotchinga chamagazi-muubongo, ndipo imapangidwa ndi dopa decarboxylase ndikusinthidwa kukhala dopamine, yomwe imagwira ntchito. Amagwiritsidwa ntchito pochiza matenda amtundu woyamba komanso matenda osagwirizana ndi mankhwala osokoneza bongo. Zimakhala ndi zotsatira zabwino kwa okalamba ocheperako komanso ofatsa, okhwima kapena osauka.

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