N-Boc-N'-trityl-L-glutamine (CAS# 132388-69-3)

WGK Germany	3
HS kodi	29242990

N-Boc-N '-trityl-L-glutamine (N-Boc-N'-trityl-L-glutamine, yofupikitsidwa ngati Boc-Gln(Trt)-OH) ndi mankhwala achilengedwe. Lili ndi zotsatirazi: 1. Maonekedwe: ufa woyera wa crystalline.
2. chilinganizo cha maselo: C39H35N3O6
3. Kulemera kwa molekyulu: 641.71g/mol
4. Malo osungunuka: 148-151°C
5. Kusungunuka: Kusungunuka muzitsulo zambiri za organic, monga dimethyl sulfoxide (DMSO) ndi dichloromethane.
6. Kukhazikika: kukhazikika pansi pamikhalidwe yoyesera.

Mu kaphatikizidwe ka mankhwala, N-Boc-N '-trityl-L-glutamine nthawi zambiri amagwiritsidwa ntchito ngati gulu loteteza amino acid kapena apakatikati. Ntchito zake zazikulu ndi izi:

1. amagwiritsidwa ntchito ngati gulu loteteza glutamine mu peptide ndi kaphatikizidwe ka mapuloteni.
2. Pakufufuza kwa mankhwala opangira mankhwala, amagwiritsidwa ntchito popanga ma analogi a glutamine.
3. amagwiritsidwa ntchito ngati wapakatikati popanga ma organic mankhwala ena.

Njira yokonzekera N-Boc-N '-trityl-L-glutamine nthawi zambiri imakhala motere:

1. Choyamba, gwiritsani ntchito N-protected glutamine (monga N-Boc-L-glutamine) ndi trityl halide (monga trityl chloride) kuti mupeze N-Boc-N '-trityl-L-glutamine.

Zambiri Zachitetezo:
N-Boc-N '-trityl-L-glutamine, monga organic pawiri, ndi otetezeka pansi kugwiritsidwa ntchito moyenera ndi kusungidwa. Komabe, zinthu zotsatirazi ziyenera kukumbukiridwa:

1. Pewani kukhudzana ndi maso, khungu ndi kupuma. Gwiritsani ntchito magolovesi oteteza mankhwala ndi magalasi.
2. Sungani pamalo ouma, ozizira.
3. Tsatirani njira zotetezera ndikuyendetsa bwino ndikutaya zinyalala zapawiri.