Papaverine Hydrochloride(CAS#61-25-6)

Papaverine Hydrochloride(CAS#61-25-6)

Papaverine hydrochloride, nambala ya CAS 61-25-6, ndi yofunika kwambiri m'munda wa mankhwala.
Kuchokera pamalingaliro azinthu zamakina, ndi mawonekedwe a hydrochloride a papaverine, ndipo kapangidwe kake kamadzimadzi kumatsimikizira katundu wake. Kapangidwe ka maatomu ndi kachitidwe ka ma khemical bond mu kapangidwe ka molekyulu kumapereka kukhazikika kwapadera ndi kuyambiranso. Maonekedwe ake nthawi zambiri amakhala oyera mpaka kuwala achikasu a crystalline ufa, omwe amathandiza kukonza, kusunga ndi kunyamula mankhwala. Pankhani ya solubility, imakhala ndi kusungunuka kwapakatikati m'madzi, ndipo malo osiyanasiyana a asidi-m'munsi ndi kutentha zidzakhudza makhalidwe ake osungunuka, omwe ndi ofunika kwambiri pakupanga mankhwala, kupanga mawonekedwe a mlingo, ndi momwe mungatsimikizire yunifolomu. kubalalitsidwa kwa mankhwala popanga jekeseni ndi kukonzekera pakamwa.
Pankhani ya mphamvu yamankhwala, Papaverine Hydrochloride ndi m'gulu la otsitsimula minofu yosalala. Imagwira makamaka pamitsempha yosalala ya mitsempha yamagazi, m'mimba, thirakiti la biliary ndi mbali zina, ndipo imalimbikitsa kupumula kwa minofu yosalala mwa kusokoneza njira monga intracellular calcium ion transport. Kachipatala, nthawi zambiri amagwiritsidwa ntchito pochiza ischemia chifukwa cha vasospasm, monga mutu ndi chizungulire chifukwa cha vasospasm ya ubongo, yomwe imatha kusintha kayendedwe ka magazi; Zimakhalanso ndi mphamvu yochepetsera ululu wa m'mimba ndi biliary colic chifukwa cha kupweteka kwa m'mimba, kuchepetsa ululu wa odwala.
Komabe, monga momwe zimakhalira ndi mankhwala ambiri, ndikofunikira kutsatira malangizo a dokotala mukamagwiritsa ntchito. Chifukwa osiyana thupi ntchito ndi maziko matenda a munthu wodwala, madokotala ayenera bwinobwino kuyeza wodwala zaka, chiwindi ndi impso ntchito, mankhwala ena akutengedwa ndi zinthu zina, ndi molondola kudziwa mlingo, njira ya makonzedwe ndi njira ya mankhwala, kotero pofuna kuonetsetsa kuti mankhwalawo ndi otetezeka komanso othandiza, komanso kuthandiza wodwalayo kuti achire. Ndi kupita patsogolo kwa kafukufuku wa sayansi, kafukufuku ndi kakulidwe ka mitundu yatsopano ya mlingo ndi kukhathamiritsa kwa mankhwala ophatikizika mozungulira akuwothanso.