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Propofol (CAS# 2078-54-8)

Chemical Property:

Molecular Formula C12H18O
Molar Misa 178.27
Kuchulukana 0.962 g/mL pa 25 °C (kuyatsa)
Melting Point 18 °C (kuyatsa)
Boling Point 256 °C/764 mmHg (kuyatsa)
Pophulikira >230°F
Kusungunuka kwamadzi Kusungunuka pang'ono m'madzi.
Kusungunuka Zomverera ndi mpweya
Kuthamanga kwa Vapor 5.6 mm Hg (100 °C)
Maonekedwe Mandala madzi
Mtundu Yellow Yotuwa mpaka Yellow
Merck 14,7834
Mtengo wa BRN 1866484
pKa pKa 11.10(H2O,t =20)(pafupifupi)
Mkhalidwe Wosungira 2-8 ° C

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Ngozi ndi Chitetezo

Zizindikiro Zowopsa R22 - Zowopsa ngati zitamezedwa
R36/37/38 - Zokwiyitsa maso, kupuma komanso khungu.
R20/21/22 - Zowopsa pokoka mpweya, kukhudzana ndi khungu komanso kumeza.
R39/23/24/25 -
R23/24/25 – Poizoni pokoka mpweya, kukhudzana ndi khungu komanso kummeza.
R11 - Yoyaka Kwambiri
Kufotokozera Zachitetezo S26 - Mukakhudza maso, yambani nthawi yomweyo ndi madzi ambiri ndikupempha uphungu wachipatala.
S36/37/39 - Valani zovala zodzitchinjiriza zoyenera, magolovesi ndi chitetezo chamaso / kumaso.
S37/39 - Valani magolovesi oyenera komanso chitetezo chamaso / kumaso
S36 - Valani zovala zoyenera zodzitetezera.
S45 - Pakachitika ngozi kapena ngati simukumva bwino, funsani upangiri wachipatala nthawi yomweyo (onetsani chizindikirocho ngati kuli kotheka.)
S36/37 - Valani zovala zoyenera zodzitchinjiriza ndi magolovesi.
S16 - Khalani kutali ndi magwero oyatsira.
S7 - Sungani chidebe chotsekedwa mwamphamvu.
Ma ID a UN 2810
WGK Germany 3
Mtengo wa RTECS Mtengo wa SL0810000
TSCA Inde
HS kodi 29089990
Kalasi Yowopsa 6.1(b)
Packing Group III

 

 

Propofol (CAS # 2078-54-8) Zambiri

khalidwe
Zamadzimadzi zachikaso zopanda colorless zokhala ndi fungo lachilendo. Zosungunuka m'madzi ambiri osungunulira, osasungunuka m'madzi.

Njira
Propofol ikhoza kupezedwa pogwiritsa ntchito isobutylene ngati zopangira komanso kuthandizidwa ndi triphenoxy aluminium kuti alkylation ya phenol.

ntchito
Yopangidwa ndi Stuart ndipo inalembedwa ku UK mu 1986. Ndi mankhwala oletsa kupweteka kwafupipafupi, ndipo zotsatira zake zimakhala zofanana ndi za sodium thiopental, koma zotsatira zake zimakhala za 1.8 nthawi zamphamvu. Kuchita mwachangu komanso nthawi yochepa yokonza. Zotsatira za kulowetsedwa ndi zabwino, zotsatira zake zimakhala zokhazikika, palibe chodabwitsa chodabwitsa, ndipo kuya kwa anesthesia kungawongoleredwe ndi kulowetsedwa kwa mtsempha kapena ntchito zambiri, palibe kudzikundikira kwakukulu, ndipo wodwalayo akhoza kuchira mwamsanga atadzuka. Amagwiritsidwa ntchito popangira anesthesia ndikuwongolera anesthesia.


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