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(S)-(-)-1 2-Diaminopropane dihydrochloride (CAS# 19777-66-3) Chithunzi Chowonetsedwa
  • (S)-(-)-1 2-Diaminopropane dihydrochloride (CAS# 19777-66-3) 1

(S)-(-)-1 2-Diaminopropane dihydrochloride (CAS# 19777-66-3)

Chemical Property:

Molecular Formula C3H12Cl2N2
Molar Misa 147.05
Melting Point 238-243 ° C
Boling Point 215.8°C pa 760 mmHg
Kuzungulira Kwapadera (α) -4 º (c=20 mu H2O)
Pophulikira 84.3°C
Kusungunuka kwamadzi Zosungunuka m'madzi
Kuthamanga kwa Vapor 0.12mmHg pa 25°C
Maonekedwe ufa mpaka kristalo
Mtundu Zoyera mpaka pafupifupi zoyera
Mtengo wa BRN 5740936
Mkhalidwe Wosungira M'mlengalenga, Kutentha kwa Zipinda

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Ngozi ndi Chitetezo

Zizindikiro Zowopsa R36/37/38 - Zokwiyitsa maso, kupuma komanso khungu.
R23/24/25 – Poizoni pokoka mpweya, kukhudzana ndi khungu komanso kummeza.
Kufotokozera Zachitetezo S26 - Mukakhudza maso, yambani nthawi yomweyo ndi madzi ambiri ndikupempha uphungu wachipatala.
S36 - Valani zovala zoyenera zodzitetezera.
S45 - Pakachitika ngozi kapena ngati simukumva bwino, funsani upangiri wachipatala nthawi yomweyo (onetsani chizindikirocho ngati kuli kotheka.)
S36/37/39 - Valani zovala zodzitchinjiriza zoyenera, magolovesi ndi chitetezo chamaso / kumaso.
WGK Germany 3
FLUKA BRAND F CODES 10-21
HS kodi 29212900

 

 

 

(S)-(-)-1 2-Diaminopropane dihydrochloride (CAS# 19777-66-3) Zambiri

Mwachidule (S) - (-) -diaminopropane dihydrochloride ingagwiritsidwe ntchito ngati mankhwala opangira mankhwala apakati, monga kukonzekera kwa Dexrazoxane, ndi dextrorotatory enantiomer ya antitumor drug razoxane. Kwa mankhwala oteteza mtima, chipatala cha Prevention of anthracycline anticancer mankhwala omwe amayamba chifukwa cha poizoni wa mtima ndi khansa ya m'magazi mwa ana chifukwa cha mankhwala amphamvu omwe amayamba chifukwa cha kuwonongeka kwa mtima, nthawi zambiri monga wothandizira pochiza khansa.
Gwiritsani ntchito (S) - (-) -diaminopropane Dihydrochloride ndi organic wapakatikati, akhoza kukonzekera pochita D-(-) - tartaric asidi ndi propylenediamine.
Diamine yakhala ikugwiritsidwa ntchito popanga mankhwala a chiral imidazoline
kukonzekera Kukonzekera kwa (S)-(-)-diaminopropane dihydrochloride: kuwonjezera 30.0gD-(-)-tartaric acid ndi 8.0 ml madzi ndi g(±) -1, 2-propanediamine mu botolo lochitira, sonkhezera kupasuka, kuzizira, kuwonjezera Dropwise, kutentha kunakwezedwa kuti reflux kwa maola 2 ndi oyambitsa. Kugwedeza kunayimitsidwa, ndipo kutentha kunakwezedwa mpaka 80 ° C. Kwa ola limodzi. Kenako, kutentha kunatsitsidwa pang'onopang'ono mpaka kutentha, kuyamwa kumasefedwa, ndi vacuum zouma kupeza 16.1g ya (S) -1, 2-propanediamine ditartrate. Onjezani 16.1g wa (S) -1, 2-propanediamine ditartrate ndi madzi ku botolo anachita, sungunulani ndi Kutentha, ndiyeno onjezerani njira ya 7.43g wa potaziyamu kolorayidi ndi 20ml madzi, osakaniza anawitsidwa pa 70 °c. kwa 2 hours. Pambuyo kuziziritsa, firiji analoledwa kuima crystallization. Sefayi inasefedwa ndi kuyamwa ndi kusungunuka kuti iume pansi pa kupanikizika kochepa kuti ipereke 84% G yachikasu cholimba (3), yokolola 4.02, [α] 20D = - ° (C = 1%, H2O).
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