(S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER（CAS# 91229-91-3)
Mawu Oyamba
di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate ndi pawiri amene mankhwala chilinganizo C14H23NO6. Zotsatirazi ndizofotokozera za katundu, ntchito, kukonzekera ndi chitetezo cha pawiri:
Chilengedwe:
-Maonekedwe: di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate ndi yopanda mtundu mpaka yoyera ya crystalline yolimba.
-Kusungunuka: Imasungunuka mu zosungunulira za organic monga ethanol, methanol ndi dimethyl sulfoxide.
- Malo osungunuka: Pawiriyi imasungunuka pafupifupi 104-105 ° C.
Gwiritsani ntchito:
di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate ndizochokera ku amino acid, zomwe zimagwiritsidwa ntchito ngati reagent mu kaphatikizidwe ka organic. Itha kugwiritsidwa ntchito popanga zinthu zomwe zimagwira biologically, monga mankhwala ndi zida za polima.
Njira:
Kukonzekera kwa di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate nthawi zambiri kumachitika ndi izi:
1. Sungunulani pyroglutamic acid tert-butyl ester mu dry dimethyl sulfoxide.
2. Kuchuluka koyenera kwa N,N'-dihydroxyethyl isopropanamide kunawonjezedwa ndipo kusakaniza kwake kunazizira mpaka pansi pa 0°C.
3. Onjezani di-tert-butyl carbonate pang'onopang'ono ndikusunga kutentha kwa zomwe zimasakanikirana ndi 0°C.
4. Akamaliza zimene anachita, osakaniza anachita anawonjezedwa kwa madzi kubala olimba precipitate wa di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate.
5. Chomaliza chomaliza chinapezedwa ndi masitepe a crystallization, kusefera ndi kuyanika.
Zambiri Zachitetezo:
di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate iyenera kugwiritsidwa ntchito ndikusamalidwa motsatira njira zotetezeka kuti asatengeke ndi khungu, maso ndi kupuma. Kuphatikiza apo, ziyenera kusungidwa pamalo owuma, ozizira komanso kutali ndi moto ndi okosijeni. Kuti mudziwe zambiri zokhudza chitetezo, onani Chemical Safety Data Sheet (MSDS) kapena mfundo zoyenera zoperekedwa ndi wogulitsa.
